Endoscopic‐assisted transorbital extended orbital exenteration: A multi‐institutional preclinical study

Author:

Roccuzzo Giuseppe1234ORCID,Vyskocil Erich3,Hirtler Lena4,Kandathil Sam Augustine4ORCID,Peris‐Celda Maria5,Agosti Edoardo6,Kuan Edward C.7,Wang Eric W.8,Leong Samuel9,Sharma Rishi10,Borsetto Daniele10ORCID,Herman Philippe11,Vinciguerra Alessandro11,Verillaud Benjamin11,Bresson Damien12,Taboni Stefano12ORCID,Erovic Boban M.13,Vural Alperen14,Dallan Iacopo15,Doglietto Francesco16,Schreiber Alberto17,Mattavelli Davide17ORCID,Rampinelli Vittorio17,Arosio Alberto Daniele18,Battaglia Paolo18,Valentini Marco18,Turri‐Zanoni Mario18,Pozzi Fabio19,Volpi Luca20,Bignami Maurizio20,Castelnuovo Paolo18,Nicolai Piero12,Ferrari Marco12ORCID

Affiliation:

1. Otolaryngology Section, Department of Neurosciences DNS University of Padova Padova Italy

2. Unit of Otorhinolaryngology – Head and Neck Surgery Azienda Ospedale‐Università Padova Padova Italy

3. Department of Otorhinolaryngology General Hospital and Medical University of Vienna Vienna Austria

4. Division of Anatomy, Center for Anatomy and Cell Biology Medical University of Vienna Vienna Austria

5. Department of Neurosurgery Mayo Clinic Rochester Minnesota USA

6. Division of Neurosurgery, Department of Medical and Surgical Specialties, Radiological Sciences and Public Health University of Brescia Brescia Italy

7. Department of Otolaryngology – Head & Neck Surgery University of California Irvine Irvine California USA

8. Department of Otolaryngology University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA

9. Department of Ear, Nose and Throat Liverpool University Hospitals NHS Foundation Trust Liverpool UK

10. Department of Otolaryngology, Addenbrooke's Hospital Cambridge University Hospitals NHS Foundation Trust Cambridge UK

11. Otorhinolaryngology and Skull Base Center, Hôpital Lariboisière, Assistance Publique‐Hôpitaux de Paris Université Paris Cité Paris France

12. Department of Neurosurgery, Hôpital Lariboisière Assistance Publique – Hôpitaux de Paris, Université Paris Cité Paris France

13. Institute of Head and Neck Diseases Evangelical Hospital Vienna Austria

14. Department of Otorhinolaryngology Istanbul University Cerrahpasa – Cerrahpasa Medical Faculty Istanbul Turkey

15. Department of Otolaryngology – Head and Neck Surgery Azienda Ospedaliero‐Universitaria Pisana Pisa Italy

16. Institute of Neurosurgery Catholic University School of Medicine Rome Italy

17. Unit of Otorhinolaryngology – Head and Neck Surgery, Department of Surgical Specialties, Radiological Sciences and Public Health University of Brescia Brescia Italy

18. Division of Otorhinolaryngology, Department of Biotechnology and Life Sciences University of Insubria‐Varese, ASST Sette Laghi, Ospedale di Circolo Varese Italy

19. Department of Neurosurgery ASST Sette Laghi, Ospedale di Circolo Fondazione Macchi Varese Italy

20. Department of Otolaryngology – Head and Neck Surgery, ASST Lariana, Ospedale Sant'Anna University of Insubria Como Italy

Abstract

AbstractBackgroundSinonasal malignancies with orbital invasion have dismal prognosis even when treated with orbital exenteration (OE). Sugawara et al. developed a surgical strategy called “extended‐OE (EOE),” showing encouraging outcomes. We hypothesized that a similar resection is achievable under endoscopic guidance through the exenterated orbit (endoscopic‐EOE).MethodsThe study was conducted in three institutions: University of Vienna; Mayo Clinic; University of Insubria; 48 orbital dissections were performed. A questionnaire was developed to evaluate feasibility and safety of each step, scoring from 1 to 10, (“impossible” to “easy,” and “high risk” to “low risk,” respectively), most likely complication(s) were hypothesized.ResultsThe step‐by‐step technique is thoroughly described. The questionnaire was answered by 25 anterior skull base surgeons from six countries. Mean, median, range, and interquartile range of both feasibility and safety scores are reported.ConclusionsEndoscopic‐EOE is a challenging but feasible procedure. Clinical validation is required to assess real‐life outcomes.

Publisher

Wiley

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3