The preparation of carbon-14 and tritium labelled 1-[4-(2-dimethylaminoethoxy) phenyl]-1, 2-diphenyl-1-butene [ICI 46,474, tamoxifen (nolvadex)] and the separation of cis-trans isomers 2. The synthesis of tritium labelled tamoxifen (nolvadex)
Author:
Publisher
Wiley
Subject
Organic Chemistry,Spectroscopy,Drug Discovery,Radiology, Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry
Reference11 articles.
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2. Tamoxifen in advanced breast cancer
3. New Reagent for Labeling Organic Compounds with Tritium
4. Lippman , M. Bolan , G. Huff , K. 60 1421 1429 1976
5. The binding of tamoxifen to oestrogen receptor proteins under equilibrium and non-equilibrium conditions
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1. Anti-hormonal Agents;Anticancer Therapeutics;2017-12-29
2. From ICI to AstraZeneca: the development of synthetic isotope chemistry at Alderley Park, UK;Journal of Labelled Compounds and Radiopharmaceuticals;2007
3. The pharmacology and clinical uses of tamoxifen;Pharmacology & Therapeutics;1984-01
4. The preparation of carbon-14 labelled 1-[4-(2-diethylamino-ethoxy) phenyl]-1, 2-diphenyl-2-chloroethene (clomiphene) and 1-[4-(2-(N-pyrrolidinyl) ethoxy) phenyl]-2-(4-methoxyphenyl)-2-nitro-2-phenylethene (CI-628, nitromiphene);Journal of Labelled Compounds and Radiopharmaceuticals;1983-09
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