Autosomal Recessive Cerebellar Ataxias in Europe: Frequency, Onset, and Severity in 677 Patients

Author:

Traschütz Andreas12ORCID,Adarmes‐Gomez Astrid D.34,Anheim Mathieu567,Baets Jonathan8910,Falkenburger Björn H.11,Gburek‐Augustat Janina12,Doss Sarah1314,Kamm Christoph15ORCID,Klivenyi Peter16,Grobe‐Einsler Marcus1718ORCID,Klopstock Thomas192021,Minnerop Martina222324,Münchau Alexander25ORCID,Pane Chiara26,Renaud Mathilde2728,Santorelli Filippo M.29,Schöls Ludger12,Timmann Dagmar30,Vielhaber Stefan313233,Haack Tobias B.34,van de Warrenburg Bart P.35,Zanni Ginevra36,Synofzik Matthis12ORCID

Affiliation:

1. Department of Neurodegenerative Diseases Hertie‐Institute for Clinical Brain Research and Center of Neurology, University of Tübingen Tübingen Germany

2. German Center for Neurodegenerative Diseases (DZNE) Tübingen Germany

3. Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla Seville Spain

4. Centro de Investigación Biomédica en Red Sobre Enfermedades Neurodegenerativas Madrid Spain

5. Service de Neurologie, Hôpitaux Universitaires de Strasbourg, Hôpital de Hautepierre Strasbourg France

6. Fédération de Médecine Translationnelle de Strasbourg Université de Strasbourg Strasbourg France

7. Institut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM‐U964/CNRS‐UMR7104/Université de Strasbourg Illkirch France

8. Translational Neurosciences, Faculty of Medicine and Health Sciences, UAntwerpen Antwerp Belgium

9. Laboratory of Neuromuscular Pathology Institute Born‐Bunge, University of Antwerp Antwerp Belgium

10. Neuromuscular Reference Centre, Department of Neurology Antwerp University Hospital Antwerp Belgium

11. Department of Neurology Technische Universität Dresden Dresden Germany

12. Division of Neuropaediatrics, Hospital for Children and Adolescents University of Leipzig Leipzig Germany

13. Department of Neurology Charité—Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt‐Universität zu Berlin Berlin Germany

14. Department of Neurological Sciences University of Nebraska Medical Center Omaha Nebraska USA

15. Department of Neurology University of Rostock Rostock Germany

16. Interdisciplinary Excellence Centre, Department of Neurology, Faculty of Medicine, Albert Szent‐Györgyi Clinical Center University of Szeged Szeged Hungary

17. Department of Neurology University Hospital Bonn Bonn Germany

18. German Center for Neurodegenerative Diseases Bonn Germany

19. Department of Neurology Friedrich‐Baur‐Institute, Ludwig‐Maximilians‐University of Munich Munich Germany

20. German Center for Neurodegenerative Diseases Munich Germany

21. Munich Cluster for Systems Neurology (SyNergy) Munich Germany

22. Institute of Neuroscience and Medicine (INM‐1), Research Centre Juelich Juelich Germany

23. Department of Neurology, Center for Movement Disorders and Neuromodulation, Medical Faculty & University Hospital Düsseldorf Heinrich Heine University Düsseldorf Germany

24. Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty & University Hospital Düsseldorf, Heinrich‐Heine University Düsseldorf Germany

25. Institute of Systems Motor Science, University of Lübeck Lübeck Germany

26. Department of Neurosciences, Reproductive and Odontostomatological Sciences University Federico II Naples Italy

27. Service de Génétique Clinique, CHRU de Nancy Nancy France

28. INSERM‐U1256 NGERE, Université de Lorraine Nancy France

29. IRCCS Fondazione Stella Maris Pisa Italy

30. Department of Neurology and Center for Translational Neuro‐ and Behavioral Sciences Essen University Hospital, University of Duisburg‐Essen Essen Germany

31. Department of Neurology Otto‐von‐Guericke University Magdeburg Germany

32. German Center for Neurodegenerative Diseases within the Helmholtz Association Magdeburg Germany

33. Center for Behavioral Brain Sciences Magdeburg Germany

34. Institute of Medical Genetics and Applied Genomics, University of Tübingen Tübingen Germany

35. Department of Neurology Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Centre Nijmegen The Netherlands

36. Unit of Neuromuscular and Neurodegenerative Disorders, Department of Neurosciences Bambino Gesù Childrens' Hospital, IRCCS Rome Italy

Funder

Bundesministerium für Bildung und Forschung

Deutsche Forschungsgemeinschaft

Fonds Wetenschappelijk Onderzoek

Horizon 2020 Framework Programme

Ministero della Salute

Publisher

Wiley

Subject

Neurology (clinical),Neurology

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