DNA methyltransferase 1/3a overexpression in sporadic breast cancer is associated with reduced expression of estrogen receptor-alpha/breast cancer susceptibility gene 1 and poor prognosis-Reference-Cited by-同舟云学术

DNA methyltransferase 1/3a overexpression in sporadic breast cancer is associated with reduced expression of estrogen receptor-alpha/breast cancer susceptibility gene 1 and poor prognosis

Published:2014-01-25 Issue:9 Volume:54 Page:707-719
ISSN:0899-1987
Container-title:Molecular Carcinogenesis
language:en
Short-container-title:Mol. Carcinog.

Author:

Yu Zhaojin¹,Xiao Qinghuan¹,Zhao Lin¹,Ren Jie¹,Bai Xuefeng¹,Sun Mingli¹,Wu Huizhe¹,Liu Xiaojian¹²,Song Zhiguo¹,Yan Yuanyuan¹,Mi Xiaoyi³⁴,Wang Enhua³⁴,Jin Feng⁵,Wei Minjie¹⁴

Affiliation:

1. Department of Pharmacology; School of Pharmaceutical Sciences, China Medical University; Shenyang China

2. Department of Pharmacology; Basic Medical College, Liaoning Medical University; Jinzhou China

3. Department of Pathology; College of Basic Medical Sciences, China Medical University; Shenyang China

4. Institute of Pathology and Pathophysiology; China Medical University; Shenyang China

5. Department of Surgical Oncology; The First Affiliated Hospital of China Medical University; Shenyang China

Funder

National Natural Science Foundation of China

Liaoning S&T Projects

Shenyang Technology Projects

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/mc.22133/fullpdf

Reference43 articles.

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3. A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation;Datta;Cancer Res,2009

4. Hormonal therapy promotes hormone-resistant phenotype by increasing DNMT activity and expression in prostate cancer models;Gravina;Endocrinology,2011

5. Epigenetic drug discovery: Targeting DNA methyltransferases;Foulks;J Biomol Screen,2012

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