Heterozygous p53 knockout mouse model for dehydropyrrolizidine alkaloid-induced carcinogenesis

Author:

Brown Ammon W.1,Stegelmeier Bryan L.1,Colegate Steven M.1,Panter Kip E.1,Knoppel Edward L.1,Hall Jeffery O.2

Affiliation:

1. USDA/ARS Poisonous Plant Research Laboratory; Logan UT USA

2. Utah Veterinary Diagnostic Laboratory; Utah State University; Logan UT USA

Funder

U.S. Department of Agriculture

Publisher

Wiley

Subject

Toxicology

Reference34 articles.

1. The structure of riddelliine, the alkaloid in Senecio riddellii;Adams;I. J. Am. Chem. Soc.,1942

2. Dehydroretronecine-induced rhabdomyosarcomas in rats;Allen;Cancer Res.,1975

3. VI. - An investigation of the hepatotoxic effects in the fowl of ragwort (Senecio jacobaea Linn.), with special reference to the induction of liver tumours with seneciphylline;Campbell;Proc. R. Soc. Edinb. [Biol.],1956

4. Chan P 2001 NTP Technical Report on Toxicology and carcinogenesis Studies of Riddelline (CAS No. 23246-96-0) in F344/N Rats and B6C3F1 Mice

5. Toxicity and carcinogenicity of riddelliine in rats and mice;Chan;Toxicol. Lett.,2003

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