CD3+TCRαβ/CD19+‐depleted stem cell boost and CD45RO+ memory T‐cell add‐back as a successful salvage treatment for poor graft function unresponsive to eltrombopag, following a second allogenic HSCT-Reference-Cited by-同舟云学术

CD3⁺TCRαβ/CD19⁺‐depleted stem cell boost and CD45RO⁺ memory T‐cell add‐back as a successful salvage treatment for poor graft function unresponsive to eltrombopag, following a second allogenic HSCT

Published:2024-07-15 Issue:10 Volume:71 Page:
ISSN:1545-5009
Container-title:Pediatric Blood & Cancer
language:en
Short-container-title:Pediatric Blood & Cancer

Author:

Ramanathan Subramaniam¹²,Roberts Wing¹²,Nademi Zohreh¹³,Shenton Geoff²,Watson Helen⁴,Matthews Emma⁵,Carruthers Kayleigh⁵,Gennery Andrew R.¹³,Hambleton Sophie¹³,Slatter Mary¹³,Lum Su Han¹³

Affiliation:

1. Department of Paediatric Haematopoietic Stem Cell Transplant Great North Children's Hospital, Royal Victoria Infirmary Newcastle upon Tyne UK

2. Department of Paediatric and Adolescent Haematology and Oncology Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust Newcastle upon Tyne UK

3. Translational and Clinical Research Institute Newcastle University Newcastle upon Tyne UK

4. Blood Sciences Newcastle upon Tyne Hospital NHS Foundation Trust Newcastle upon Tyne UK

5. Newcastle Advanced Therapies Newcastle upon Tyne Hospital NHS Foundation Trust Newcastle upon Tyne UK

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/pbc.31203

Reference9 articles.

1. Clinical features, pathophysiology and therapy of Poor Graft Function Post Allogeneic Stem Cell Transplantation

2. Eltrombopag maintains human hematopoietic stem and progenitor cells under inflammatory conditions mediated by IFN-γ

3. CD34 Stem Cell Boost in Pediatric Allogeneic Stem Cell Transplant Recipients: A Case Series and Review of Literature

4. Durable Engraftment and Excellent Overall Survival After CD34-Selected Peripheral Blood Stem Cell Boost in Pediatric Patients With Poor Graft Function Following Allogeneic Stem Cell Transplantation

5. Boost of CD34+‐selected peripheral blood cells without further conditioning in patients with poor graft function following allogeneic stem cell transplantation;Larocca A;Haematologica,2006