Correlation of pre-operative plasma protein concentrations in cardiac surgery patients with bleeding outcomes using a targeted quantitative proteomics approach

Author:

Clendenen Nathan1,Tollefson Ashley12,Dzieciatkowska Monika3,Cambiaghi Alice4,Ferrario Manuela4,Kroehl Miranda5,Banerjee Anirban6,D'Alessandro Angelo3,Hansen Kirk C.3,Weitzel Nathaen1

Affiliation:

1. Department of Anesthesiology; University of Colorado Denver; Aurora CO USA

2. Medical School; University of Minnesota; Minneapolis MN USA

3. Department of Biochemistry and Molecular Genetics; University of Colorado Denver; Aurora CO USA

4. Politecnico di Milano; Milan Italy

5. Department of Biostatistics and Informatics; University of Colorado Denver; Aurora CO USA

6. Department of Surgery; University of Colorado Denver; Aurora CO USA

Funder

National Blood Foundation

National Institute of General Medical Sciences

Publisher

Wiley

Subject

Clinical Biochemistry

Reference44 articles.

1. Platelet mapping as part of modified thromboelastography (TEG®) in patients undergoing cardiac surgery and cardiopulmonary bypass;Weitzel;Anaesthesia,2012

2. The operating surgeon is an independent predictor of chest tube drainage following cardiac surgery;Dixon;J. Cardiothorac. Vasc. Anesth.,2014

3. Use of recombinant activated factor VII in cardiac surgery for an effective treatment of severe intractable bleeding;Vanek;Jpn. Heart J.,2004

4. Factors associated with excessive postoperative blood loss and hemostatic transfusion requirements: a multivariate analysis in cardiac surgical patients;Despotis;Anesth. Analg.,1996

5. Thromboelastography-guided transfusion algorithm reduces transfusions in complex cardiac surgery;Shore-Lesserson;Anesth. Analg.,1999

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