Tumor-associated mutations inO6-methylguanine DNA-methyltransferase (MGMT) reduce DNA repair functionality-Reference-Cited by-同舟云学术

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Tumor-associated mutations inO6-methylguanine DNA-methyltransferase (MGMT) reduce DNA repair functionality

Published:2012-10-12 Issue:3 Volume:53 Page:201-210
ISSN:0899-1987
Container-title:Molecular Carcinogenesis
language:en
Short-container-title:Mol. Carcinog.

Author:

Lamb Kristy L.¹²,Liu Yanfeng¹,Ishiguro Kimiko³,Kwon Youngho⁴,Paquet Nicolas⁴,Sartorelli Alan C.³,Sung Patrick¹⁴,Rockwell Sara¹³,Sweasy Joann B.¹²

Affiliation:

1. Department of Therapeutic Radiology; Yale University School of Medicine; New Haven Connecticut

2. Department of Genetics; Yale University School of Medicine; New Haven Connecticut

3. Department of Pharmacology; Yale University School of Medicine; New Haven Connecticut

4. Department of Molecular Biophysics and Biochemistry; Yale University School of Medicine; New Haven Connecticut

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

Reference46 articles.

1. Genetic variation at the human MGMT locus and its biological consequences;Margison;Curr Pharmacogen,2006

2. Alkylation damage in DNA and RNA-repair mechanisms and medical significance;Drablos;DNA Repair,2004

3. Repair of O(6)-alkylguanine by alkyltransferases;Pegg;Mutat Res,2000

4. Human variants of O6-alkylguanine-DNA alkyltransferase;Pegg;DNA Repair,2007

5. O6-alkylguanine-DNA alkyltransferase;Pegg;Chem Carcinog: Curr Cancer Res,2011

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