Synthesis of dialkyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylates and alkyl 1,4-dihydro-2,6-dimethyl-3-nitropyridine-5-carboxylates possessing a c-4 2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl (uracil) substituent to determine calcium channel modulation structure-activity relationships-Reference-Cited by-同舟云学术

Synthesis of dialkyl 1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylates and alkyl 1,4-dihydro-2,6-dimethyl-3-nitropyridine-5-carboxylates possessing a c-4 2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl (uracil) substituent to determine calcium channel modulation structure-activity relationships

Published:2004-03 Issue:2 Volume:41 Page:263-266
ISSN:0022-152X
Container-title:Journal of Heterocyclic Chemistry
language:en
Short-container-title:

Author:

Fassihi Afshin,Velazquez Carlos,Knaus Edward E.

Publisher

Wiley

Subject

Organic Chemistry

Reference26 articles.

1. Calcium channels: Structure, function, and classification

2. New developments in calcium ion channel antagonists

3. Crystal structures of calcium channel antagonists: 2,6-dimethyl-3,5-dicarbomethoxy-4-[2-nitro-, 3-cyano-, 4-(dimethylamino)-, and 2,3,4,5,6-pentafluorophenyl]-1,4-dihydropyridine

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis, calcium-channel blocking activity, and conformational analysis of some novel 1,4-dihydropyridines: application of PM3 and DFT computational methods;Medicinal Chemistry Research;2011-10-20

2. Miscellaneous Name Reactions;Name Reactions in Heterocyclic Chemistry II;2011-10-07

3. Facile Synthesis and Antibacterial, Antitubercular, and Anticancer Activities of Novel 1,4-Dihydropyridines;Archiv der Pharmazie;2010-06-08

4. Synthesis of sterically hindered 3,5,5-trimethyl 2,6-dioxo tetrahydro pyrimidine as HCV protease inhibitors;Tetrahedron Letters;2010-03

5. Advances in the Synthesis of 5- and 6-Substituted Uracil Derivatives;Organic Preparations and Procedures International;2009-11-20