1. Ring transformation of 4-amino-1H-1,5-benzodiazepine-3-carbonitrile. The use of hydroxylamines as nucleophile.
2. Ring transformation of 4-amino-1H-1,5-benzodiazepine-3-carbonitrile. II. Formation of ring-opened hydrazine adducts.
3. The pyrimidino[4,5-b][1,5]benzodiazepin-5-one derivatives, prepared by condensation of a 4-chloropyrimidine with o-phenylenediamines, were reported to be useful as inhibitors of stomach and intestinal ulcers and of gastric secretions: H. Schaefer, R. Riedel, K. Klemm, J. Senn-Bilfinger and M. Eltze, European Patent Appl., 24,582 (1981);
4. Chem. Abstr., 95, 132969u (1981).