Diversity in theandrogen receptorCAG repeat has been shaped by a multistep mutational mechanism

Author:

Santos Diana1,Pimenta João1,Wong Virginia CN2,Amorim António13,Martins Sandra1

Affiliation:

1. IPATIMUP; Institute of Molecular Pathology and Immunology of the University of Porto; Porto Portugal

2. Department of Pediatrics and Adolescent Medicine; The University of Hong Kong; Hong Kong China

3. Faculdade de Ciências; Universidade do Porto; Porto Portugal

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience,Psychiatry and Mental health,Genetics(clinical)

Reference24 articles.

1. Structural and functional consequences of glutamine tract variation in the androgen receptor;Buchanan;Hum Mol Genet,2004

2. Implications of a polyglutamine tract in the function of the human androgen receptor;Callewaert;Biochem Biophys Res Commun,2003

3. Reduced androgen receptor gene expression with first exon CAG repeat expansion;Choong;Mol Endocrinol,1996

4. Arlequin (version 3.0): An integrated software package for population genetics data analysis;Excoffier;Evol Bioinform Online,2005

5. Variable tandem repeats accelerate evolution of coding and regulatory sequences;Gemayel;Annu Rev Genet,2010

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