Chemical constituents and cytotoxicity of <i>Lepidotrigona ventralis</i> propolis-Reference-Cited by-同舟云学术

Chemical constituents and cytotoxicity of Lepidotrigona ventralis propolis

Published:2023-01-27 Issue:1 Volume:61 Page:74-79
ISSN:2572-8288
Container-title:Vietnam Journal of Chemistry
language:en
Short-container-title:Vietnam Journal of Chemistry

Author:

Thanh Le Nguyen¹,Thu Nguyen Anh¹,Oanh Vu Thi Kim¹,Hue Vu Thi¹,Minh Nguyen Tu²,Minh Nguyen Phan Ngoc²,Xuan Truong Vinh²,Phuong Diep Thi Lan³,Lien Nguyen Thi Phuong⁴

Affiliation:

1. Graduate University of Science and Technology, Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST) 18 Hoang Quoc Viet, Cau Giay Hanoi 10000 Viet Nam

2. GATE Center, Vinschool T37‐458 Minh Khai Hanoi 10000 Viet Nam

3. Faculty of Sciences, Quy Nhon University 170 An Duong Vuong, Quy Nhon, Binh Dinh 55000 Viet Nam

4. Institute of Ecological and Biological Resouces, VAST 18 Hoang Quoc Viet, Cau Giay Hanoi 10000 Viet Nam

Abstract

AbstractFrom propolis of Lepidotrigona ventralis stingless bee collected in Tuyen Quang province, eight compounds were isolated and determined as lantanolic acid (1), moronic acid (2), (+)‐eudesmin (3), (+)‐yangambin (4), (+)‐syringaresinol (5), (+)‐pinoresinol (6), dihydroconiferyl alcohol (7) and vanillin (8) using NMR and MS spectral data. Compounds 1 and 2 showed significant cytotoxicity against HepG‐2 cancer cell line with IC50 values of 25.84±0.48 and 39.92±1.14 μg/mL, respectively.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/vjch.202200031

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