The chemical composition from the fruits of Pandanus tonkinensis, their NO production inhibitory and lipid peroxidation inhibitory activities

Author:

Trang Dinh Thi Huyen12,Trang Pham Thu3,Phuong Do Minh3,Anh Duong Hong34,Anh Ngo Quoc15,Van Kiem Phan16,Viet Pham Hung3ORCID

Affiliation:

1. Graduate University of Science and Technology, VAST 18 Hoang Quoc Viet, Cau Giay Hanoi 10000 Viet Nam

2. College of Education, Vinh University 182 Le Duan, Truong Thi, Vinh City, Nghe An 43000 Viet Nam

3. Key Laboratory of Analytical Technology for Environmental Quality & Food Safety Control, University of Science, Vietnam National University, Hanoi 334 Nguyen Trai Hanoi 10000 Viet Nam

4. Research Centre for Environmental Technology and Sustainable Development, University of Science, Vietnam National University, Hanoi 334 Nguyen Trai Hanoi 10000 Viet Nam

5. Institute of Chemistry, Vietnam Academy of Science and Technology 18 Hoang Quoc Viet, Cau Giay Hanoi 10000 Viet Nam

6. Institute of Marine Biochemistry, Vietnam Academy of Science and Technology 18 Hoang Quoc Viet, Cau Giay Hanoi 10000 Viet Nam

Abstract

AbstractSeven known compounds, including two neolignans, four lignans, and one flavane were isolated from the methanol extract of Pandanus tonkinenis fruits. Their structures were determined to be ficusal (1), vladinol F (2), medioresinol (3), syringaresinol (4), lariciresinol (5), secoisolariciresinol (6), and luteoliflavan (7) by analysis of MS and NMR data as well as by comparison of their spectral data with those reported in the literature. All compounds were evaluated for NO production inhibitory and lipid peroxidative inhibitory activities. Compounds 5 and 7 showed significant NO production inhibitory with IC50 values of 5.3±0.4 and 7.1±0.4 μM, respectively. Compounds 6 and 7 showed significant lipid peroxidative inhibitory activity with IC50 values of 20.2±1.7 and 26.2±3.6 μM, respectively.

Publisher

Wiley

Reference15 articles.

1. Chemical constituents from the chloroform extract of the fruit of Pandanus kaida Kurz (Pandanaceae);Chuc L. T. N.;Vietnam J. Anal. Sci.,2013

2. Extraction of some phenolic compounds from the fruit of Pandanus odoratissimus L.f;Cuong N. M.;Vietnam J. Chem.,2015

3. A new dihydrofurocoumarin from the fruits of Pandanus tectorius Parkinson ex Du Roi

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