An efficient synthesis of acridine‐aza‐anthraquinone hybrid compounds under microwave irradiation

Abstract

AbstractThe efficient synthesis of 12‐substituted‐3,4,4a,5,12,12a‐hexahydrobenzo[b]acridine‐1,6,11(2H)‐triones starting from 2‐amino‐1,4‐naphthoquinone, 1,3‐cyclohexanedione, and different (hetero)aromatic aldehydes was developed. These reactions were carried out in acetic acid under microwave irradiation in the presence of p‐toluenesulfonic acid as catalyst. The structure of the newly synthesized compounds were confirmed employing spectroscopic data as well as elemental analysis. The plausible mechanism of these three‐component domino reactions was also described.