Lung ultrasound score in the decision of patent ductus arteriosus closure in neonates

Author:

Ozdemir Mustafa1ORCID,Tepe Tugay1ORCID,Ozlu Ferda1ORCID,Yapicioglu Hacer1ORCID,Atmıs Anıl2ORCID,Demir Fadli2ORCID,Unal Ilker3ORCID,Narli Nejat1ORCID

Affiliation:

1. Faculty of Medicine, Department of Pediatrics, Division of Neonatology Cukurova University Adana Turkey

2. Faculty of Medicine, Department of Pediatrics, Division of Pediatric Cardiology Cukurova University Adana Turkey

3. Faculty of Medicine, Department of Biostatistics Cukurova University Adana Turkey

Abstract

AbstractPurposeWe aimed to investigate the role of lung ultrasound (LUS) score in the closure of hemodynamically insignificant patent ductus arteriosus (PDA) and the clinical findings of the patients before and after closure.MethodsThe study groups (107 preterm neonates under 34 gestational weeks) were classified as hemodynamically significant PDA (group 1), hemodynamically insignificant PDA with closure therapy (group 2), hemodynamically insignificant PDA without closure therapy (group 3), and no PDA group (group 4) based on the echocardiography. 6‐ and 10‐region LUS scores were compared for each group.ResultsThere was a significant difference between groups 1 and 3 on first, third, and seventh days. In contrast, groups 1 and 2 had similar LUS scores on the first, third, and seventh days. There was a negative correlation between LUS scores on the first and third days and gestational age, birth weight, the first‐ and fifth‐minute APGAR scores, and there was a positive correlation between aortic root to left atrium ratio, and PDA diameter/weight ratio.ConclusionWe observed that LUS scores in patients with hemodynamically insignificant PDA treated with closure therapy were similar to in patients with hemodynamically significant PDA. Thus, LUS score can have role in PDA closure in preterm neonates. However, more comprehensive studies are needed.

Publisher

Wiley

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