Transpiration‐Inspired Fabric Dressing for Acceleration Healing of Wound Infected with Biofilm

Abstract

AbstractIn chronic wound management, efficacious handling of exudate and bacterial infections stands as a paramount challenge. Here a novel biomimetic fabric, inspired by the natural transpiration mechanisms in plants, is introduced. Uniquely, the fabric combines a commercial polyethylene terephthalate (PET) fabric with asymmetrically grown 1D rutile titanium dioxide (TiO2) micro/nanostructures, emulating critical plant features: hierarchically porous networks and hydrophilic water conduction channels. This structure endows the fabric with exceptional antigravity wicking‐evaporation performance, evidenced by a 780% one‐way transport capability and a 0.75 g h−1 water evaporation rate, which significantly surpasses that of conventional moisture‐wicking textiles. Moreover, the incorporated 1D rutile TiO2 micro/nanostructures present solar‐light induced antibacterial activity, crucial for disrupting and eradicating wound biofilms. The biomimetic transpiration fabric is employed to drain exudate and eradicate biofilms in Staphylococcus aureus (S. aureus)‐infected wounds, demonstrating a much faster infection eradication capability compared to clinically common ciprofloxacin irrigation. These findings illuminate the path for developing high‐performance, textile‐based wound dressings, offering efficient clinical platforms to combat biofilms associated with chronic wounds.