Activation via the antigen receptor is impaired in T cells, but not in B cells from patients with common variable immunodeficiency
Author:
Publisher
Wiley
Subject
Immunology,Immunology and Allergy
Reference24 articles.
1. Failure in antigen responses by T ceils from patients with common variable immunodeficiency (CVID)
2. Defects in antigen-driven lymphocyte responses in common variable immunodeficiency (CVID) are due to a reduction in the number of antigen-specific CD4+ T cells
3. Defective interleukin-2 and interferon-γ gene expression in response to antigen in a subgroup of patients with common variable immunodeficiency
4. A defect in the early phase of T-cell receptor-mediated T-cell activation in patients with common variable immunodeficiency
5. The costimulatory signal CD28 is fully functional but cannot correct the impaired antigen response in T cells of patients with common variable immunodeficiency
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