Two Cryptic Self‐Resistance Mechanisms in Streptomyces tenebrarius Reveal Insights into the Biosynthesis of Apramycin-Reference-Cited by-同舟云学术

Two Cryptic Self‐Resistance Mechanisms in Streptomyces tenebrarius Reveal Insights into the Biosynthesis of Apramycin

Published:2021-03-05 Issue:16 Volume:60 Page:8990-8996
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Zhang Qian¹,Chi Hao‐Tian¹,Wu Linrui¹,Deng Zixin¹,Yu Yi¹^ORCID

Affiliation:

1. Key Laboratory of Combinatory Biosynthesis and Drug Discovery (Ministry of Education) School of Pharmaceutical Sciences Wuhan University Wuhan 430071 China

Funder

National Key Research and Development Program of China

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202100687

Reference59 articles.

1. The Classic: Streptomycin, a Substance Exhibiting Antibiotic Activity against Gram-Positive and Gram-Negative Bacteria

2. Biosynthetic genes for aminoglycoside antibiotics

4. Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

5. Molecular recognition of aminoglycoside antibiotics by ribosomal RNA and resistance enzymes: An analysis of x-ray crystal structures

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Intracellularly driven chemical modifications of antimicrobial secondary metabolites: Potent mechanisms of self-resistance;Pharmaceutical Science Advances;2024-12

2. Improving the production of carbamoyltobramycin by an industrial Streptoalloteichus tenebrarius through metabolic engineering;Applied Microbiology and Biotechnology;2024-04-21

3. Complete In Vitro Reconstitution of the Apramycin Biosynthetic Pathway Demonstrates the Unusual Incorporation of a β-d-Sugar Nucleotide in the Final Glycosylation Step;Journal of the American Chemical Society;2024-03-28

4. Dissection of 3D chromosome organization in Streptomyces coelicolor A3(2) leads to biosynthetic gene cluster overexpression;Proceedings of the National Academy of Sciences;2023-03-06

5. Newly Discovered Mechanisms of Antibiotic Self-Resistance with Multiple Enzymes Acting at Different Locations and Stages;Antibiotics;2022-12-26