Cross‐Module Enoylreduction in the Azalomycin F Polyketide Synthase-Reference-Cited by-同舟云学术

Cross‐Module Enoylreduction in the Azalomycin F Polyketide Synthase

Published:2020-10-08 Issue:50 Volume:59 Page:22738-22742
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Zhai Guifa¹,Wang Wenyan²,Xu Wei¹³,Sun Guo¹,Hu Chaoqun¹,Wu Xiangming¹,Cong Zisong²,Deng Liang¹,Shi Yanrong¹,Leadlay Peter F.⁴,Song Heng²,Hong Kui¹,Deng Zixin¹,Sun Yuhui¹^ORCID

Affiliation:

1. Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Wuhan University) Ministry of Education, and School of Pharmaceutical Sciences Wuhan University No. 185 East Lake Road Wuhan 430071 P. R. China

2. College of Chemistry and Molecular Sciences Wuhan University No. 299 Bayi Road Wuhan 430072 P. R. China

3. Current address: Singapore Institute of Food and Biotechnology Innovation Agency for Science, Technology, and Research (A*STAR) Singapore Singapore

4. Department of Biochemistry University of Cambridge No. 80 Tennis Court Road Cambridge CB2 1GA UK

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202011357

Reference35 articles.

1. Structure and mechanism of assembly line polyketide synthases

2. An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

3. Modular organization of genes required for complex polyketide biosynthesis

4. Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis

5. Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

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