Recent advances in biopolymer based electrospun nanomaterials for drug delivery systems

Author:

Tören Elçin12ORCID,Buzgo Matej2,Mazari Adnan Ahmed1,Khan Muhammad Zaman1ORCID

Affiliation:

1. Faculty of Textile Engineering Technical University of Liberec Liberec Czech Republic

2. RnD RESPILON Membranes S.R.O Brno‐střed Czech Republic

Abstract

AbstractDrug delivery systems, including liposomes, gels, prodrugs, and so forth, are used to enhance the tissue benefit of a pharmaceutical drug or conventional substance at a specific diseased site with little toxicological impact. Nanotechnology can be a rapidly developing multidisciplinary science that enables the production of polymers at the manometer scale for different medical applications. The use of biopolymers in drug delivery systems provides compatibility, biodegradability and low immunogenicity biologically. Large‐scale and smaller‐than‐expected medication particles can be delivered using biopolymers such as silk fibroins, collagen, gelatine, and others that are easily formed into suspensions. These drug carrier systems are functional at improving drug delivery and can be used in intranasal, transdermal, dental, and ocular delivery systems. This study discusses the latest developments in drug delivery methods based on nanomaterials, mainly using biopolymers like proteins and polysaccharides.

Funder

Technická Univerzita v Liberci

Publisher

Wiley

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