Genomic profiling reveals the pivotal role of hrHPV driving copy number and gene expression alterations, including mRNA downregulation of TP53 and RB1 in penile cancer-Reference-Cited by-同舟云学术

Genomic profiling reveals the pivotal role of hrHPV driving copy number and gene expression alterations, including mRNA downregulation of TP53 and RB1 in penile cancer

Published:2020-03-24 Issue:6 Volume:59 Page:604-617
ISSN:0899-1987
Container-title:Molecular Carcinogenesis
language:en
Short-container-title:Mol Carcinog

Author:

Macedo Juliana¹,Silva Elis²,Nogueira Leudivan³,Coelho Ronald³,Silva Jenilson¹²,Santos Alcione⁴,Teixeira‐Júnior Antônio Augusto⁵,Belfort Marta¹,Silva Gyl⁵,Khayat André⁶,Oliveira Edivaldo⁷,dos Santos Ana Paula⁸,Cavalli Luciane R.⁹¹⁰,Pereira Silma Regina²^ORCID

Affiliation:

1. Postgraduate Program in Health Science, Federal University of Maranhão São Luís Maranhão Brazil

2. Laboratory of Genetics and Molecular Biology, Department of BiologyFederal University of MaranhãoSão Luís Maranhão Brazil

3. Aldenora Bello Cancer HospitalSão Luís Maranhão Brazil

4. Public Health DepartmentFederal University of MaranhãoSão Luís Maranhão Brazil

5. Biology Undergraduate Course, Department of PathologyFederal University of MaranhãoSão Luís Maranhão Brazil

6. Oncology Research CenterFederal University of ParáBelém Pará Brazil

7. Tissue Culture and Cytogenetics LaboratoryInstitute of Evandro ChagasBelém Pará Brazil

8. Department of Physiological SciencesFederal University of MaranhãoSão Luís Maranhão Brazil

9. Faculdades Pequeno Príncipe, Instituto de Pesquisa Pelé Pequeno PríncipeCuritiba Paraná Brazil

10. Department of OncologyGeorgetown Lombardi Comprehensive Cancer CenterWashington District of Columbia United States

Funder

Fundação de Amparo à Pesquisa e ao Desenvolvimento Científico e Tecnológico do Maranhão

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/mc.23185

Reference73 articles.

1. Relationship between human papillomavirus and penile cancer—implications for prevention and treatment

2. Updates in the molecular epidemiology and systemic approaches to penile cancer

3. Epidemiology of penile cancer

4. Penile cancer in Maranhão, Northeast Brazil: the highest incidence globally?

5. Profile of patients with penile cancer in the region with the highest worldwide incidence

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