Levetiracetam add-on for drug-resistant focal epilepsy

Author:

Mbizvo Gashirai K12,Chandrasekar Bharath3,Nevitt Sarah J4,Dixon Pete5,Hutton Jane L6,Marson Anthony G157

Affiliation:

1. The Walton Centre NHS Foundation Trust; Liverpool UK

2. Muir Maxwell Epilepsy Centre, Centre for Clinical Brain Sciences, University of Edinburgh; Edinburgh UK

3. University of Liverpool; Liverpool UK

4. Department of Biostatistics; University of Liverpool; Liverpool UK

5. Department of Molecular and Clinical Pharmacology; Institute of Translational Medicine, University of Liverpool; Liverpool UK

6. Department of Statistics; University of Warwick; Coventry UK

7. Liverpool Health Partners; Liverpool UK

Publisher

Wiley

Subject

Pharmacology (medical)

Reference72 articles.

1. Efficacy and tolerability of levetiracetam 3000 mg/d in patients with refractory partial seizures: a multicenter, double-blind, responder-selected study evaluating monotherapy. European Levetiracetam Study Group;Ben-Menachem;Epilepsia,2000

2. Evaluation of the efficacy and tolerability of UCB L059 (1500 mg b.i.d., 500 mg tablets) monotherapy in epileptic patients with complex partial onset seizures, having experienced improved seizure control under add-on treatment: a 60-week (maximum), double-blind, multicenter, responder-selected trial (phase III study, placebo comparator) UCB S.A. Pharma Sector

3. A multicentre, double-blind, randomized, parallel group study to evaluate the tolerability and efficacy of two oral doses of levetiracetam, 2000 mg daily and 4000 mg daily, without titration in patients with refractory epilepsy;Betts;Seizure,2000

4. A 24-week multicentered, double-blind, parallel group, add-on study to compare the efficacy and the tolerability of 2 oral daily doses of UCB L059 (2000 mg and 4000 mg tablets) with placebo in patients with refractory epilepsy, followed by a 24-week open-label active treatment UCB S.A. Pharma Sector

5. Levetiracetam for partial seizures: results of a double-blind, randomized clinical trial;Cereghino;Neurology,2000

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