Simultaneous determination of nine lignans from Schisandra chinensis extract using ultra-performance liquid chromatography with tandem mass spectrometry in rat plasma, urine, and gastrointestinal tract samples: Application to the pharmacokinetic study of-Reference-Cited by-同舟云学术

Simultaneous determination of nine lignans from Schisandra chinensis extract using ultra-performance liquid chromatography with tandem mass spectrometry in rat plasma, urine, and gastrointestinal tract samples: Application to the pharmacokinetic study of

Published:2014-09-16 Issue:20 Volume:37 Page:2851-2863
ISSN:1615-9306
Container-title:Journal of Separation Science
language:en
Short-container-title:J. Sep. Science

Author:

Kim You-Jin¹,Lee Hee Ju²,Kim Chul Young³,Han Sun-Young⁴,Chin Young-Won¹,Choi Young Hee¹

Affiliation:

1. College of Pharmacy and BK21PLUS R-FIND team; Dongguk University-Seoul; Goyang South Korea

2. Functional Food Center; KIST Gangneung Institute; Gangneung Republic of Korea

3. College of Pharmacy and Institute of Pharmaceutical Science and Technology; Hanyang University; Ansan Republic of Korea

4. College of Pharmacy and Research Institute of Pharmaceutical Sciences; Gyeongsang National University; Jinju Republic of Korea

Funder

This study was supported by the Dongguk University Research Foundation Fund of 2010

Publisher

Wiley

Subject

Filtration and Separation,Analytical Chemistry

Reference24 articles.

1. Rapid determination and pharmacokinetics study of lignans in rat plasma after oral administration of Schisandra chinensis extract and pure deoxyschisandrin

2. Study on the plasma protein binding rate of Schisandra lignans based on the LC-IT-TOF/MS technique with relative quantitative analysis

3. Chemical analysis of twelve lignans in the fruit of Schisandra sphenanthera by HPLC–PAD-MS

4. Application of ultrahigh-performance liquid chromatography coupled with mass spectrometry for analysis of lignans and quality control of Fructus Schisandrae chinensis

5. Development of a Systematic Approach to Identify Metabolites for Herbal Homologs Based on Liquid Chromatography Hybrid Ion Trap Time-of-Flight Mass Spectrometry: Gender-Related Difference in Metabolism of SchisandraLignans in Rats

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