The AUA/SUFU guideline on the diagnosis and treatment of idiopathic overactive bladder

Author:

Cameron Anne P.1,Chung Doreen E.2,Dielubanza Elodi J.3,Enemchukwu Ekene4,Ginsberg David A.5,Helfand Brian T.6,Linder Brian J.7,Reynolds W. Stuart8,Rovner Eric S.9,Souter Lesley10,Suskind Anne M.11,Takacs Elizabeth12,Welk Blayne13,Smith Ariana L.14

Affiliation:

1. Department of Urology University of Michigan Ann Arbor Michigan

2. Department of Urology Columbia University New York New York

3. Department of Urology University of Southern California Palo Alto California

4. Department of Urology Stanford University School of Medicine Palo Alto California

5. Department of Urology University of Southern California Los Angeles California

6. Northshore Health System Glenview Illinois

7. Department of Urology Mayo Clinic Rochester Minnesota

8. Department of Urology Vanderbilt University Medical Center Nashville Tennessee

9. Department of Urology Medical University of South Carolina Charleston South Carolina

10. Nomadic EBM Methodology Smithville Ontario Canada

11. Department of Urology University of California, San Francisco San Francisco California

12. Mason City Clinic Mason City Iowa

13. Department of Surgery and Epidemiology & Biostatistics Western University London Ontario Canada

14. Division of Urology University of Pennsylvania Philadelphia Pennsylvania

Abstract

AbstractPurposeThe purpose of this guideline is to provide evidence‐based guidance to clinicians of all specialties on the evaluation, management, and treatment of idiopathic overactive bladder (OAB). The guideline informs the reader on valid diagnostic processes and provides an approach to selecting treatment options for patients with OAB through the shared decision‐making process, which will maximize symptom control and quality of life, while minimizing adverse events and burden of disease.MethodsAn electronic search employing OVID was used to systematically search the MEDLINE and EMBASE databases, as well as the Cochrane Library, for systematic reviews and primary studies evaluating diagnosis and treatment of OAB from January 2013 to November 2023. Criteria for inclusion and exclusion of studies were based on the Key Questions and the populations, interventions, comparators, outcomes, timing, types of studies and settings (PICOTS) of interest. Following the study selection process, 159 studies were included and were used to inform evidence‐based recommendation statements.ResultsThis guideline produced 33 statements that cover the evaluation and diagnosis of the patient with symptoms suggestive of OAB; the treatment options for patients with OAB, including Noninvasive therapies, pharmacotherapy, minimally invasive therapies, invasive therapies, and indwelling catheters; and the management of patients with BPH and OAB.ConclusionOnce the diagnosis of OAB is made, the clinician and the patient with OAB have a variety of treatment options to choose from and should, through shared decision‐making, formulate a personalized treatment approach taking into account evidence‐based recommendations as well as patient values and preferences.

Publisher

Wiley

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