Docosahexaenoic acid promotes cell cycle arrest and decreases proliferation through WNT/β-catenin modulation in colorectal cancer cells exposed to γ-radiation

Author:

Murad Leonardo Borges1,da Silva Nogueira Perôny1,de Araújo Wallace Martins1,Sousa-Squiavinato Annie Cristhine Moraes1,Rocha Murilo Ramos1,de Souza Waldemir Fernandes1,de-Freitas-Junior Júlio1,Barcellos-de-Souza Pedro1,Bastos Lilian Gonçalves1,Morgado-Díaz Jose Andrés1ORCID

Affiliation:

1. Cellular and Molecular Oncobiology Program; Brazilian National Cancer Institute; Rio de Janeiro RJ Brazil

Funder

Conselho Nacional de Desenvolvimento Cientifico e Tecnológico

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado de Rio de Janeiro

Instituto Nacional de Ciência e Tecnologia em Câncer

Publisher

Wiley

Subject

Clinical Biochemistry,Molecular Medicine,General Medicine,Biochemistry

Reference50 articles.

1. Global cancer statistics, 2012;Torre;CA Cancer J. Clin.,2015

2. Recently published indicators allow for comparison of radiation treatment rates relative to evidence-based guidelines for rectal cancer;Rahal;Curr. Oncol. Tor. Ont.,2012

3. Cancer invasion and resistance: interconnected processes of disease progression and therapy failure;Alexander;Trends Mol. Med.,2012

4. Radiation-induced signaling pathways that promote cancer cell survival (review);Hein;Int. J. Oncol.,2014

5. Overexpression of nuclear β-catenin in rectal adenocarcinoma is associated with radioresistance;Wang;World J. Gastroenterol.,2013

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