Use of Monte Carlo simulations for improved facility fit planning in downstream biomanufacturing and technology transfer
Author:
Affiliation:
1. Biologics Process Development Bristol Myers Squibb Company Summit New Jersey USA
2. Biologics Process Development Bristol Myers Squibb Company Devens Massachusetts USA
Publisher
Wiley
Subject
Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/btpr.3306
Reference19 articles.
1. Biomanufacturing evolution from conventional to intensified processes for productivity improvement: a case study
2. Process intensification in fed-batch production bioreactors using non-perfusion seed cultures
3. Data mining for rapid prediction of facility fit and debottlenecking of biomanufacturing facilities
4. Exploration of overloaded cation exchange chromatography for monoclonal antibody purification;Liu HF;J Chromatogr A,2011
5. Recovery and purification process development for monoclonal antibody production
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