Phase 1 study to access safety, tolerability, pharmacokinetics, and pharmacodynamics of kynurenine in healthy volunteers-Reference-Cited by-同舟云学术

Phase 1 study to access safety, tolerability, pharmacokinetics, and pharmacodynamics of kynurenine in healthy volunteers

Published:2021-03-07 Issue:2 Volume:9 Page:
ISSN:2052-1707
Container-title:Pharmacology Research & Perspectives
language:en
Short-container-title:Pharmacol Res Perspect

Author:

Al‐Karagholi Mohammad Al‐Mahdi¹^ORCID,Hansen Jakob Møller¹²,Abou‐Kassem Dalia¹,Hansted Anna Koldbro³^ORCID,Ubhayasekera Kumari⁴,Bergquist Jonas⁴,Vécsei László⁵,Jansen‐Olesen Inger³,Ashina Messoud¹²

Affiliation:

1. Danish Headache Center Department of Neurology University of Copenhagen Denmark

2. Danish Knowledge Center on Headache Disorders Rigshospitalet‐Glostrup Denmark

3. Danish Headache Center Glostrup Research Institute Rigshospitalet Glostrup Faculty of Health and Medical Sciences University of Copenhagen Denmark

4. Analytical Chemistry and Neurochemistry Department of Chemistry ‐ BMC Uppsala University Sweden

5. Department of Neurology and MTA‐SZTE Neuroscience Research Group University of Szeged Szeged Hungary

Funder

Candys Foundation

Lundbeckfonden

Publisher

Wiley

Subject

General Pharmacology, Toxicology and Pharmaceutics,Neurology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prp2.741

Reference49 articles.

1. Endogenous kynurenines as targets for drug discovery and development

2. Tryptophan Nutrition and Metabolism: An Overview

3. Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway

4. The role of kynurenines in disorders of the central nervous system: Possibilities for neuroprotection

5. Kynurenine as an Intermediate in the Formation of Nicotinic Acid from Tryptophane by Neurospora

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