Dual agent chemoprotection by retroviral co-expression of either MDR1 or MRP1 with the P140K mutant ofO6-methylguanine-DNA-methyl transferase
Author:
Publisher
Wiley
Subject
Genetics (clinical),Drug Discovery,Genetics,Molecular Biology,Molecular Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/jgm.914/fullpdf
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3. A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents
4. Efficient protection of cells from the genotoxicity of nitrosoureas by the retrovirus-mediated transfer of human O6-methylguanine-DNA methyltransferase using bicistronic vectors with human multidrug resistance gene 1
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1. Chemoprotection of murine hematopoietic cells by combined gene transfer of cytidine deaminase (CDD) and multidrug resistance 1 gene (MDR1);Journal of Experimental & Clinical Cancer Research;2015-12
2. Clinical Trials Using LV-P140K-MGMT for Gliomas;Gene Therapy of Cancer;2014
3. Gene therapy in pancreatic cancer;World Journal of Gastroenterology;2014
4. F2A sequence linking MGMTP140K and MDR1 in a bicistronic lentiviral vector enables efficient chemoprotection of haematopoietic stem cells;Cancer Gene Therapy;2012-10-05
5. Chemoprotection of human hematopoietic stem cells by simultaneous lentiviral overexpression of multidrug resistance 1 and O6-methylguanine-DNA methyltransferaseP140K;Gene Therapy;2009-10-29
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