Unravelling lung adenocarcinoma in an immunocompetent patient with endobronchial aspergilloma: A case report

Author:

Ng Khai Lip1ORCID,Huan Nai‐Chien2ORCID,Tan Wei Loon1,Aminudin Nur Husna Mohd1,Hassan Fazilah3,Nordin Kasuma Mohamed1

Affiliation:

1. Division of Respiratory Medicine, Department of Medicine Melaka Hospital Melaka Malaysia

2. Department of Respiratory Medicine Queen Elizabeth Hospital Kota Kinabalu Malaysia

3. Department of Pathology Melaka Hospital Melaka Malaysia

Abstract

AbstractInhalation of Aspergillus spp. can cause a wide spectrum of lung diseases. Endobronchial aspergilloma is an uncommon clinical entity that occurs because of Aspergillus spp. overgrowth in the airway lumen. We present a 73‐year‐old gentleman with a rare dual pathology of endobronchial aspergilloma and endobronchial adenocarcinoma. He initially presented with prolonged cough, dyspnoea, and haemoptysis. Bronchoscopy revealed an obstructed right main bronchus by a necrotic mass whereby histological examination showed evidence of Aspergillus spp. infection. The lesion however persisted despite treatment with anti‐fungal agents. Repeated bronchoscopy and biopsy eventually unravelled an underlying endobronchial adenocarcinoma. He received chemotherapy but ultimately passed away 3 months later.

Publisher

Wiley

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1. Amphotericin-B/Voriconazole;Reactions Weekly;2024-09-07

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