In VitroMetabolism in Preclinical Drug Development

Author:

Pelkonen Olavi,Tolonen Ari,Turpeinen Miia,Uusitalo Jouko

Publisher

John Wiley & Sons, Inc.

Reference101 articles.

1. In vitro screening of drug metabolism during drug development: Can we trust the predictions;Pelkonen;Expert Opin Drug Metab Toxicol,2005

2. Role of pharmacokinetics and metabolism in drug discovery and development;Lin;Pharmacol Rev,1997

3. ADMET in silico modelling: towards prediction paradise;Van de Waterbeemd;Nat Rev Drug Dev,2003

4. Human cytochrome P450 enzymes (human CYPs): human cytochrome P450 enzymes, a status report summarizing their reactions, substrates, inducers, and inhibitors-1st update;Guengerich;Drug Metab Rev,2002

5. Metabolism: a bottleneck in in vitro toxicological test development. The Report and Recommendations of ECVAM Workshop 54;Coecke;Altern Lab Anim,2006

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