Dual silencing of EGFR and HER2 enhances the sensitivity of gastric cancer cells to gefitinib

Author:

Wang Liying1,Zhang Hongfeng2,Zheng Jiaxin3,Wei Xiaoli4,Du Jingwen4,Lu Haibo4,Sun Qiuying4,Zhou Weiyu4,Zhang Rui5,Han Yu4ORCID

Affiliation:

1. Department of Oncology; Chaoyang Central Hospital; Chaoyang Liaoning Province China

2. Department of Gastric Surgery; Harbin Medical University Cancer Hospital; Harbin Heilongjiang Province China

3. Department of Nephrology; Heilongjiang Academy of Traditional Chinese Medicine; Harbin Heilongjiang Province China

4. Department of Gastrointestinal Oncology; Harbin Medical University Cancer Hospital; Harbin Heilongjiang Province China

5. Department of Colorectal Surgery; Cancer Hospital of China Medical University; Liaoning Cancer Hospital and Institute; Shenyang Liaoning Province China

Funder

Department of Education, Heilongjiang Province

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

Reference41 articles.

1. Global cancer statistics;Torre;CA Cancer J Clin,2012

2. Gastric cancer: pathogenesis, screening and treatment;Sugano;Gastrointest Endosc Clin N Am,2008

3. Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 Study Group;Van Cutsem;J Clin Oncol,2006

4. Capecitabine and oxaliplatin for advanced esophagogastric cancer;Cunningham;N Engl J Med,2008

5. Chemotherapy for advanced gastric cancer;Wagner;Cochrane Database Syst Rev,2010

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