Affiliation:
1. Key Laboratory of Structure-Based Drug Design & Discovery Ministry of Education School of Traditional Chinese Materia Medica Shenyang Pharmaceutical University Shenyang 110016 China
Abstract
AbstractFrom Garcinia pedunculata Roxb. fruits, two undescribed aromatic compounds including a benzofuran and a depsidone derivative, and a new natural product, together with four known compounds were isolated. Through the analysis of spectroscopic data, high resolution mass spectrum and calculated nuclear magnetic resonance, their structures were determined. The α‐glucosidase inhibitory activity of the isolates was evaluated. And compound 3 exhibited a moderate inhibitory effect on α‐glucosidase. The molecular docking of compound 3 was performed to elucidate the interaction with α‐glucosidase.
Funder
National Natural Science Foundation of China