Exploring the Pharmacognostical and Phytochemical Profiles of Aqueous Extracts of Kalanchoe

Author:

Machinski Isadora1,Andrade Evelyn Assis1,Schaffka Vinicius Monteiro2,de Almeida Valter Paes1,Santos Aline3,Bueno Debora3,Perera Wilmer Hervet4,Pereira Romaiana Picada2,Manfron Jane13,Miyoshi Edmar3,Beltrame Flávio Luís13ORCID

Affiliation:

1. Pharmaceutical Sciences Graduate Program State University of Ponta Grossa Ponta Grossa PR Brazil

2. Department of Chemistry State University of Ponta Grossa Ponta Grossa PR Brazil

3. Department of Pharmaceutical Sciences State University of Ponta Grossa Ponta Grossa PR Brazil

4. CAMAG Scientific Inc. 515 Cornelius Harnett Drive Wilmington NC 28401 USA

Abstract

AbstractThe use of plants for medicinal purposes has a long history, however it is desirable a continuous evaluation seeking for complementary scientific evidences for their safe application. Species within the Kalanchoe genus are often referred to as “miracle leaf” due to their remarkable healing properties. Traditionally, these plants have been used to treat infections, inflammation, and cancer. Despite their widespread use, the identification of their active components remains incomplete. This study aimed to differentiate K. crenata (KC), K. marmorata (KM), and K. pinnata (KP) by conducting detailed histochemical and phytochemical analyses, and to assess their antioxidant capabilities. The investigation revealed significant differences between the species, highlighting the variability in phenolic (PC) and flavonoid contents (FC) and their distinct antioxidant effects. The KM demonstrated the greatest results (PC: 59.26±1.53 mgEqGA/g; FC: 12.63±0.91 mgEqCQ/g; DPPH⋅ (IC50): 110.66 ug/mL; ABTS⋅+ (IC50): 26.81 ug/mL; ORAC: 9.65±0.75 mmolTE) when compared to KC and KP. These findings underscore a new reference for research within the Kalanchoe genus.

Publisher

Wiley

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