The Inhibitory Activity of Natural Products to Xanthine Oxidase

Author:

Zhou Shiyang12,Huang Gangliang1ORCID

Affiliation:

1. Key Laboratory of Carbohydrate Science and Engineering College of Chemistry Chongqing Normal University Chongqing 401331 China

2. School of Environmental and Quality Testing Chongqing Chemical Industry Vocational College Chongqing 401228 China

Abstract

AbstractThe natural products have a new chemical structure and biological active diversity, so they are favored by scientific researchers. Gout is a high incidence and high‐risk disease, and the current treatments are not satisfactory. Xanthine oxidase (XO) is a key enzyme responsible for the development and progression of various metabolic and oxidative stress‐related diseases. Excessive activity of XO leads to elevated serum urate levels, which in turn leads to the development of hyperuricemia. This review mainly introduces the recent progress of the new research on the anti‐gout activity of natural products that could provide new treatment methods for gout and information for the discovery and development of new anti‐gout drugs.

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

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