A Review on Torilis japonica: Ethnomedicinal, Phytochemical, and Biological Features

Author:

Rahimpour Yahya1,Doorandishan Mina2,Dehsheikh Anahita Boveiri3,Sourestani Mohammad Mahmoodi3,Mottaghipisheh Javad45ORCID

Affiliation:

1. Student Research Committee Tabriz University of Medical Sciences Tabriz Iran

2. Department of Chemistry Faculty of Sciences Golestan University Gorgan Iran

3. Department of Horticultural Science Faculty of Agriculture Shahid Chamran University of Ahvaz Ahvaz Iran

4. Center for Molecular Biosciences (CMBI) Institute of Pharmacy/Pharmacognosy University of Innsbruck Innrain 80–82 6020 Innsbruck Austria

5. Department of Aquatic Sciences and Assessment Swedish University of Agricultural Sciences (SLU) SE-750 07 Uppsala Sweden

Abstract

AbstractThe present study was aimed at comprehensive overviewing a phytochemically and biologically important species namely Torilis japonica (Apiaceae family). Treatment of dysentery, fever, haemorrhoids, spasm, uterine tumors, lymphadenitis, rheumatism, impotence, infertility, women's diseases, and chronic diarrhea are reported as the main folk medicinal applications of the T. japonica fruits. So far, the plant is phytochemically characterized for its diverse terpene derivatives, predominantly sesquiterpenes. The plant's fruit is a rich source of torlin, a guaiane‐type sesquiterpene, possessing various potent bioactivities. To date, anticancer, anti‐inflammatory, antimicrobial, antioxidant, skin photoaging activities of the plant extracts and its constituents have been evaluated. Further investigation of the plant, specifically bioassay‐guided isolation and identification of its major bioactive constituents can lead to discover potential phytopharmaceutical candidates.

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

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