Five New Furostanol Glycosides from the Fruits of <i>Tribulus terrestris</i> with NO Production Inhibitory Activity-Reference-Cited by-同舟云学术

Five New Furostanol Glycosides from the Fruits of Tribulus terrestris with NO Production Inhibitory Activity

Published:2024-07-16 Issue:9 Volume:21 Page:
ISSN:1612-1872
Container-title:Chemistry & Biodiversity
language:en
Short-container-title:Chemistry & Biodiversity

Author:

Kiem Phan Van¹^ORCID,Quoc Nguyen Van²,Tai Bui Huu¹,Yen Pham Hai¹,Huy Hoang Nguyen¹,Thi Thuy Hang Dan¹,Huong Phan Thi Thanh¹,Anh Bang Ngo¹,Dung Duong Thi¹,Trang Do Thi¹,Giang Le Duc³

Affiliation:

1. Institute of Marine Biochemistry VAST 18 Hoang Quoc Viet Cau Giay, Hanoi 10072 Vietnam

2. School of Chemistry Biology and Environment Vinh University 182 Le Duan Ben Thuy, Vinh City Nghe An 461010 Vietnam

3. Department of Chemistry Vinh University 182 Le Duan Ben Thuy, Vinh City Nghe An 461010 Vietnam

Abstract

AbstractEight furostanol glycosides including five undescribed compounds, named tribufurostanosides A–E (1–5), and three known ones (6–8) were isolated from the fruits of Tribulus terrestris L. Their chemical structures were determined by the IR, HR‐ESI‐MS, 1D‐, and 2D‐NMR spectra. Furostanols 1–8 significantly inhibited nitric oxide production in LPS activated RAW 264.7 cells with IC50 values ranging from 14.2 to 64.7 μM, compared to that of the positive control compound, dexamethazone (IC50 13.6 μM).

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbdv.202401273

Reference30 articles.

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