Development of novel PET probe [11C](R,R)HAPT and its stereoisomer [11C](S,S)HAPT for vesicular acetylcholine transporter imaging: A PET study in conscious monkey
Author:
Affiliation:
1. Central Research Laboratory, Hamamatsu Photonics K.K., Hamakita; Hamamatsu Shizuoka Japan
2. Life Science Research Group, NARD Institute, Ltd.; Chuo-ku, Kobe Hyogo Japan
3. Corporate Research Group, NARD Institute, Ltd.; Chuo-ku, Kobe Hyogo Japan
Publisher
Wiley
Subject
Cellular and Molecular Neuroscience
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/syn.21743/fullpdf
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4. Vesamicol and some of its derivatives: Questionable ligands for selectively labelling acetylcholine transporters in rat brain;Custers;Eur J Pharmacol,1997
5. Palladium(0)-mediated rapid methylation and fluoromethylation on carbon frameworks by reacting methyl and fluoromethyl iodide with aryl and alkenyl boronic acid esters: Useful for the synthesis of [11C]CH3-C and [18F]FCH2-C-containing PET tracers;Doi;Chem Eur J,2009
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1. In Vivo and In Vitro Characteristics of Radiolabeled Vesamicol Analogs as the Vesicular Acetylcholine Transporter Imaging Agents;Contrast Media & Molecular Imaging;2018-06-13
2. Kinetic modeling of [ 18 F]V AT , a novel radioligand for positron emission tomography imaging vesicular acetylcholine transporter in non‐human primate brain;Journal of Neurochemistry;2018-03
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4. Synthesis and in vitro evaluation of 5-substituted benzovesamicol analogs containing N-substituted amides as potential positron emission tomography tracers for the vesicular acetylcholine transporter;Bioorganic & Medicinal Chemistry;2017-10
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