From ICI to AstraZeneca: the development of synthetic isotope chemistry at Alderley Park, UK
Author:
Publisher
Wiley
Subject
Organic Chemistry,Spectroscopy,Drug Discovery,Radiology, Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry
Reference23 articles.
1. The preparation and purification of labelled β-adrenergic blocking agents. Part I. Synthesis of carbon-14 and tritium labelled 1-isopropylamino-3-(1-naphthyloxy)-propan-2-ol hydrochloride, (propranolol hydrochloride, inderal
2. Low-Temperature Fluorography Induced by Tritium-Labelled Compounds on Thin-Layer Chromatograms
3. The preparation of carbon-14 and tritium labelled 1-[4-(2-dimethylaminoethoxy) phenyl]-1, 2-diphenyl-1-butene [ICI 46,474, tamoxifen (nolvadex)] and the separation of cis-trans isomers 2. The synthesis of tritium labelled tamoxifen (nolvadex)
4. Preparation of carbon-14 labelled ethyl 2-(P-chlorophenoxy)-2-methyl propionate (CLofibrate; atromid-S); clofibric acid and clofibric amide
5. Synthesis and purification of carbon-14 labelled 1, 1-hexamethylene-bis [5-(4-chlorophenyl)biguanide] (chlorhexidine), ‘Hibitane’
Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Expeditious syntheses of stable and radioactive isotope-labeled anticonvulsant agent, JNJ-26990990, and its metabolites;Journal of Labelled Compounds and Radiopharmaceuticals;2013-01
2. Glucuronides from metabolites to medicines: a survey of the in vivo generation, chemical synthesis and properties of glucuronides;Natural Product Reports;2013
3. 50th anniversary special issue, in memoriam John Jones;Journal of Labelled Compounds and Radiopharmaceuticals;2007
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