Elderly POSSUM, a dedicated score for prediction of mortality and morbidity after major colorectal surgery in older patients

Author:

Tran Ba Loc P1,Tezenas du Montcel S12,Duron J J3,Levard H4,Suc B5,Descottes B6,Desrousseaux B7,Hay J M8

Affiliation:

1. Biostatistics and Medical Information Unit, Groupe Hospitalier Pitié–Salpêtrière, Assistance Publique–Hôpitaux de Paris, Paris, France

2. Pierre and Marie Curie Paris 6 University, Er 4 (former EA3974), Modelling in Clinical Research, Pierre and Marie Curie Paris 6 University, Paris, France

3. Digestive Surgery and Transplantation Unit, Groupe Hospitalier Pitié–Salpêtrière, Assistance Publique–Hôpitaux de Paris, Paris, France

4. General and Digestive Surgery Unit, Institut Monsouris, Paris, France

5. Digestive Surgery Unit, Centre Hospitalier Universitaire de Rangueil, Rangueil, France

6. Visceral Surgery and Transplantation Unit, Centre Hospitalier Universitaire de Limoges, Limoges, France

7. General and Digestive Surgery Unit, Centre Hospitalier General de Lomme, Lomme, France

8. General and Digestive Surgery Unit, Hôpital Louis Mourier, Assistance Publique–Hôpitaux de Paris, Paris, France

Abstract

Abstract Background Several scores have been developed to evaluate surgical unit mortality and morbidity. The Physiological and Operative Severity Score for the enUmeration of Mortality and morbidity (POSSUM) and derivatives use preoperative and intraoperative factors, whereas the Surgical Risk Scale (SRS) and Association Française de Chirurgie (AFC) score use four simple factors. To allow for advanced age in patients undergoing colorectal surgery, a dedicated score—the Elderly (E) POSSUM—has been developed and its accuracy compared with these scores. Methods From 2002 to 2004, 1186 elderly patients, at least 65 years old, undergoing major colorectal surgery in France were enrolled. Accuracy was assessed by calculating the area under the receiver operating characteristic curve (AUC) (discrimination) and calibration. Results The mortality and morbidity rates were 9 and 41 per cent respectively. The E-POSSUM had both a good discrimination (AUC = 0·86) and good calibration (P = 0·178) in predicting mortality and a reasonable discrimination (AUC = 0·77) and good calibration (P = 0·166) in predicting morbidity. The E-POSSUM was significantly better at predicting mortality and morbidity than the AFC score (Pc = 0·014 and Pc < 0·001 respectively). Conclusion The E-POSSUM is a good tool for predicting mortality, and the only efficient scoring system for predicting morbidity after major colorectal surgery in the elderly.

Funder

Haute Autorité de Santé

Programme Hospitalier de Recherche Clinique (PHRC) Appel d'Offre Régional

Ligue Nationale contre le Cancer

Publisher

Oxford University Press (OUP)

Subject

Surgery

Reference37 articles.

1. Centre for Health Development. 2001;World Health Organization

2. Elderly patients in surgical workloads: a population-based analysis;Etzioni;Am Surg,2003

3. Postoperative complications and mortality in older patients having non-cardiac surgery at three Melbourne teaching hospitals;McNicol;Med J Aust,2007

4. Impact of age on perioperative complications and length of stay in patients undergoing noncardiac surgery;Polanczyk;Ann Intern Med,2001

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