A metabolite of daidzein, 6,7,4′-trihydroxyisoflavone, suppresses adipogenesis in 3T3-L1 preadipocytes via ATP-competitive inhibition of PI3K-Reference-Cited by-同舟云学术

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A metabolite of daidzein, 6,7,4′-trihydroxyisoflavone, suppresses adipogenesis in 3T3-L1 preadipocytes via ATP-competitive inhibition of PI3K

Published:2013-06-04 Issue:8 Volume:57 Page:1446-1455
ISSN:1613-4125
Container-title:Molecular Nutrition & Food Research
language:en
Short-container-title:Mol. Nutr. Food Res.

Author:

Seo Sang Gwon¹²,Yang Hee¹,Shin Seung Ho¹,Min Soyun¹,Kim Yeong A.¹,Yu Jae Gak¹,Lee Dong Eun¹,Chung Min-Yu¹,Heo Yong-Seok³,Kwon Jung Yeon⁴,Yue Shuhua⁵,Kim Kee Hong⁴,Cheng Ji-Xin⁵⁶,Lee Ki Won¹²,Lee Hyong Joo¹²

Affiliation:

1. WCU Biomodulation Major, Center for Food and Bioconvergence; Department of Agricultural Biotechnology, Seoul National University; Seoul Republic of Korea

2. Advanced Institutes of Convergence Technology; Seoul National University; Suwon Republic of Korea

3. Department of Chemistry, Konkuk University; Seoul Republic of Korea

4. Department of Food Science, Purdue University; West Lafayette IN USA

5. Weldon School of Biomedical Engineering; Purdue University; West Lafayette IN USA

6. Department of Chemistry, Purdue University; West Lafayette IN USA

Funder

National Research Foundation of Korea

Korea government

Next-Generation BioGreen 21 Program

Publisher

Wiley

Subject

Food Science,Biotechnology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/mnfr.201200593/fullpdf

Reference43 articles.

1. From multipotent stem cell to adipocyte;Lane;Birth Defects Res. A Clin. Mol. Teratol.,2005

2. Dominant-negative C/EBP disrupts mitotic clonal expansion and differentiation of 3T3-L1 preadipocytes;Zhang;Proc. Natl. Acad. Sci. USA,2004

3. Mitotic clonal expansion: a synchronous process required for adipogenesis;Tang;Proc. Natl. Acad. Sci. USA,2003

4. Cell line models for differentiation: preadipocytes and adipocytes;Poulos;Exp. Biol. Med. (Maywood),2010

5. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells;Cao;Genes Dev.,1991

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