Synthesis, Profiling, and Bioactive Conformation of trans ‐Cyclopropyl Epothilones

Author:

Kuzniewski Christian N.1,Glauser Simon1,Gaugaz Fabienne Z.1,Schiess Raphael1,Rodríguez‐Salarichs Javier2,Vetterli Stefan1,Horlacher Oliver P.1,Gertsch Jürg3,Redondo‐Horcajo Mariano2,Canales Angeles4,Jiménez‐Barbero Jesús567,Díaz José Fernando2,Altmann Karl‐Heinz1ORCID

Affiliation:

1. Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical SciencesETH Zürich Vladimir-Prelog-Weg 4, HCI H405 CH-8093 Zürich

2. Centro de Investigaciones BiológicasConsejo Superior de Investigaciones Científicas, C/Ramiro de Maeztu 9 ES-28040 Madrid Spain

3. Institute of Biochemistry and Molecular MedicineUniversity of Bern Bühlstrasse 28 CH-3012 Bern Switzerland

4. Departamento de Química Orgánica I, Facultad de Ciencias QuímicasUniversidad Complutense de Madrid Av. Complutense ES-28040 Madrid Spain

5. CIC bioGUNE, Asociación Centro de Investigación Cooperativa en BiocienciasBizkaia Science and Technology Park building 801A ES-48160 Derio, Bizkaia Spain

6. IkerbasqueBasque Foundation for Science Maria Diaz de Haro 3, 6 solairua ES-48013 Bilbao, Bizkaia Spain

7. Department of Organic Chemistry II, Faculty of Science & TechnologyUniversity of the Basque Country, Barrio Sarriena s/n ES-48940 Leioa, Bizkaia Spain

Publisher

Wiley

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Drug Discovery,Biochemistry,Catalysis

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