Errors in translation act as a “tipping point” leading to the onset of neurodegenerative disease
Author:
Affiliation:
1. Purdue University West Lafayette Indiana USA
Publisher
Wiley
Subject
General Biochemistry, Genetics and Molecular Biology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/bies.202300081
Reference5 articles.
1. Hallmarks of neurodegenerative diseases
2. Adapting the proteostasis capacity to sustain brain healthspan
3. To aggregate or not to aggregate – Is it a matter of the ribosome?
4. Cockayne Syndrome-Associated CSA and CSB Mutations Impair Ribosome Biogenesis, Ribosomal Protein Stability, and Global Protein Folding
5. Error-prone protein synthesis recapitulates early symptoms of Alzheimer disease in aging mice
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1. The central role of transfer RNAs in mistranslation;Journal of Biological Chemistry;2024-09
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