Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicity-Reference-Cited by-同舟云学术

Increased PARP1-DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1-DNA trapping is correlated with PARP1 inhibitor's cytotoxicity

Published:2019-01-30 Issue:3 Volume:145 Page:714-727
ISSN:0020-7136
Container-title:International Journal of Cancer
language:en
Short-container-title:Int. J. Cancer

Author:

Chen Hua-Dong¹²^ORCID,Chen Chuan-Huizi¹²,Wang Yu-Ting¹²,Guo Ne¹²,Tian Yu-Nan¹²,Huan Xia-Juan¹²,Song Shan-Shan¹²,He Jin-Xue¹²,Miao Ze-Hong¹²³

Affiliation:

1. Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research; Shanghai Institute of Materia Medica, Chinese Academy of Sciences; Shanghai China

2. University of Chinese Academy of Sciences; Beijing China

3. Open Studio for Druggability Research of Marine Natural Products; Pilot National Laboratory for Marine Science and Technology (Qingdao); Qingdao China

Funder

Science and Technology Commission of Shanghai Municipality

Chinese Academy of Sciences

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cancer Research,Oncology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/ijc.32131/fullpdf

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