Oncofertility care for children, adolescents, and young adults at risk for treatment‐related fertility loss

Author:

Talbot Lindsay1ORCID,Corkum Kristine S.2,McCracken Kate3,Cost Nicholas G.4ORCID,Aldrink Jennifer H.5ORCID

Affiliation:

1. Department of Surgery St. Jude Children's Research Hospital Memphis Tennessee USA

2. Division of Pediatric Surgery Department of Surgery, and the Surgical Oncology Program Children's Hospital of Colorado University of Colorado School of Medicine Aurora Colorado USA

3. Section of Pediatric and Adolescent Gynecology Division of Gynecology Department of Obstetrics and Gynecology C. S. Mott Children's Hospital University of Michigan Ann Arbor Michigan USA

4. Division of Pediatric Urology Department of Urology, and the Surgical Oncology Program Children's Hospital of Colorado University of Colorado School of Medicine Aurora Colorado USA

5. Division of Pediatric Surgery Department of Surgery Nationwide Children's Hospital The Ohio State University College of Medicine Columbus Ohio USA

Abstract

AbstractAs therapy for childhood malignancies becomes more sophisticated and survival has improved, long‐term therapy‐related sequelae have emerged. Loss of reproductive potential among childhood cancer survivors is one such concern that has become increasingly recognized among patients, families, and healthcare providers. The risk status for infertility based upon therapy received, state of current reproductive technology and outcomes, and an emphasis on adequate referral and counseling for fertility preservation options are reviewed. Contributing factors to infertility are discussed, and options for female and male preservation based upon age and pubertal status are summarized. This article highlights the current state of fertility opportunities for children and adolescents undergoing therapy for cancer. Providers caring for these young patients should be familiar with such options and should routinely initiate evaluations for eligibility of fertility preservation.

Publisher

Wiley

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