Distribution of the follicular and luteal phase lengths and their age‐dependent changes in Japanese women: A large population study

Author:

Mitake Sawa1,Wada‐Hiraike Osamu2ORCID,Kashiwabara Kosuke3,Nakamura Akari4,Nasu Risa4,Hine Maaya4,Matsuyama Yutaka3,Fujii Tomoyuki2,Osuga Yutaka2ORCID

Affiliation:

1. The University of Tokyo Tokyo Japan

2. Department of Obstetrics and Gynecology, Graduate School of Medicine The University of Tokyo Tokyo Japan

3. Department of Biostatistics, School of Public Health, Graduate School of Medicine The University of Tokyo Tokyo Japan

4. Department of Healthcare Business MTI Ltd. Tokyo Japan

Abstract

AbstractPurposeThe current definition of menstrual cycle length in a Japanese woman is different from those of WHO definition, and the original data are outdated. We aimed to calculate the distribution of follicular and luteal phases length in modern Japanese women with various menstrual cycles.MethodsThis study determined the lengths of the follicular and luteal phases of Japanese women using basal body temperature data collected via a smartphone application from 2015 to 2019, and the data were analyzed using the Sensiplan method. Over 9 million temperature readings from more than 80 000 participants were analyzed.ResultsThe mean duration of the low‐temperature (follicular) phase averaged 17.1 days and was shorter among participants aged 40–49 years. The mean duration of the high‐temperature (luteal) phase was 11.8 days. The variance and maximum‐minimum difference of the length of the low temperature period were significant in women under 35 years old than women aged more than 35 years.ConclusionsThe shortening of the follicular phase in women aged 40–49 years implied a relationship with the rapid decline of ovarian reserve in these women, and the age 35 years old was turning point of ovulatory function.

Funder

Ministry of Health, Labour and Welfare

Publisher

Wiley

Subject

Cell Biology,Reproductive Medicine

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