A modification to improve the reliability of [11 C]CN− production in the GE radiochemistry system

Author:

Labaree David C.1ORCID,Ropchan Jim R.1ORCID,Nabulsi Nabeel1ORCID,Huang Yiyun1ORCID

Affiliation:

1. Yale PET Center, Department of Radiology and Biomedical Imaging; Yale University School of Medicine; New Haven Connecticut USA

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology, Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Reference29 articles.

1. The synthesis of radioactive lactic acid;Cramer;J Biol Chem,1941

2. Routine production of H11CN and [11C]-1-Aminocyclopentanecarboxylic acid;Sambre;Int J Appl Radiat Isot,1985

3. Synthesis of 1- and 3-11C-labelled L-lactic acid using multi-enzyme catalysis;Bjurling;J Label Compd Radiopharm,1990

4. Synthesis of 1-11C-labeled fatty acid from [11C]HCN;Takahashi;Int J Appl Radiat Isot,1990

5. On-column preparation of 1-aminocyclopentane-1-[11C]carboxylic acid;Iwata;Int J Appl Radiat Isot,1995

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1. Gas Phase Transformations in Carbon-11 Chemistry;International Journal of Molecular Sciences;2024-01-18

2. Evaluation and improvement of CuI‐mediated 11C‐cyanation;Journal of Labelled Compounds and Radiopharmaceuticals;2023-03

3. Automated radiosynthesis of [ 11 C]MTP38—a phosphodiesterase 7 imaging tracer—using [ 11 C]hydrogen cyanide for clinical applications;Journal of Labelled Compounds and Radiopharmaceuticals;2022-02-09

4. [ 11 C]HCN Radiochemistry: Recent Progress and Future Perspectives;European Journal of Organic Chemistry;2021-09

5. Radiochemistry with Carbon‐11;Handbook of Radiopharmaceuticals;2020-12-21

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