Abstract
The reports of infections and outbreaks due to Escherichia coli 0157:H7 have increased in the EU for the last five years. The clinical spectrum of the infection varies from hemorrhagic colitis, hemolytic-uremic syndrome (HUS) and rarely, thrombotic thrombocytopenic purpura. This infection is new to Bulgaria, and we report a case of VT1 and VT2 positive E. coli O157:H7 with the presentation of this organism with the onset of haemorrhagic colitis, HUS and lethal exitus of the patient.
Publisher
National Center of Infectious and Parasitic Diseases
Reference10 articles.
1. Ameer MA, Wasey A, Salen P. Escherichia coli (e Coli 0157 H7) [Updated 2023 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507845/
2. Glenn Buvens, et. al. Verocytotoxin-Producing Escherichia coli Incidence and Virulence Determinants of Infections in the Brussels-Capital Region, Belgium, in 2008-2010. J. Clin. Microbiol. 2012, 50(4):1336. https://doi.org/10.1128/JCM.05317-11.
3. Piérard D. Infections with verotoxin-producing Escherichia coli. Acta Clin Belg. 1992;47(6):387-96. https://doi.org/10.1080/17843286.1992.11718260 PMID: 1337811.
4. Larry M. Bush , Maria T. Vazquez-Pertejo. Infection by Escherichia coli O157:H7 and Other Enterohemorrhagic E. coli (EHEC). 2022. https://www.msdmanuals.com/professional/infectious-diseases/gram-negative-bacilli/infection-by-escherichia-coli-o157-h7-and-other-enterohemorrhagic-e-coli-ehec
5. Griffin PM, Ostroff SM, Tauxe RV, Greene KD, Wells JG, Lewis JH, Blake PA. Illnesses associated with Escherichia coli O157:H7 infections. A broad clinical spectrum. Ann Intern Med. 1988 Nov 1;109(9):705-12. https://doi.org/10.7326/0003-4819-109-9-705 PMID: 3056169.