Author:
Hunter J. W.,Owen Susanne,Eksi Aysel,Scott J. F.
Abstract
Chemically, trimipramine has an imino-benzyl nucleus and a side-chain resembling that of methotrimeprazine [5-(3-dimethyl-amino-2-methyl-propyl)-10, 11-dihydrodibenz (b, f,) azepine]. In “double blind” controlled comparisons of trimipramine and imipramine, Salzmann (1965) in 27 hospitalized depressed patients who did not require ECT, found the two drugs not significantly different in effect. Blumenthal and Seppala (1965) obtained similar results. Burns (1965), however, in 44 patients suffering from psychotic depression, found trimipramine to be significantly superior at the 5 per cent. level to imipramine in ratings of recovery from depression, anxiety and insomnia. No difference was found in the latency interval between the drugs.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Reference9 articles.
1. Preliminary Evaluation of a New Anti-Depressant, Trimipramine, by a Sequential Method
2. A RATING SCALE FOR DEPRESSION
3. “A controlled trial with trimipramine, a new anti-depressant drug.”;Salzmann;Ibid.,1965
4. “Un nouvel anti-dépresseur sédatif dérivé de l'iminod-i-benzyle: le 7162 rp.; essais théapeutiques.”;Lambert;Presse med.,1961
5. “Mobility” in chronic schizophrenia with special regard to psychosurgery
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献