Endogenous Depression Treated with Iproniazid—A Follow-Up Study

Abstract

A double-blind controlled trial of iproniazid in endogenous depression and a comparison of its effects with those of E.C.T. was reported in this journal by Kiloh et al. (1960). To summarize the results—of 26 patients treated with iproniazid a good immediate response was found in 14 cases (54 per cent.) whereas only 3 of 28 patients (11 per cent.) given placebo tablets showed a significant improvement at the end of three weeks. Of 27 patients treated with E.C.T. 24 (89 per cent.) showed a good immediate response.