Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer

Author:

Lu Weiqiang1ORCID,Yu Weiwei1,He Jiacheng1,Liu Wenjuan1,Yang Junjie1,Lin Xianhua1,Zhang Yuanjin1,Wang Xin1ORCID,Jiang Wenhao1,Luo Jian1,Zhang Qiansen1,Yang Huaiyu1,Peng Shihong1,Yi Zhengfang1,Ren Shancheng2,Chen Jing3,Siwko Stefan4,Nussinov Ruth56,Cheng Feixiong789,Zhang Hankun1ORCID,Liu Mingyao1ORCID

Affiliation:

1. Shanghai Key Laboratory of Regulatory Biology Institute of Biomedical Sciences and School of Life Sciences East China Normal University Shanghai China

2. Department of Urology Changhai Hospital Second Military University Shanghai China

3. School of Basic Medical Sciences Ningxia Medical University Yinchuan China

4. Department of Molecular and Cellular Medicine Institute of Biosciences and Technology Texas A&M University Health Science Center Houston TX USA

5. Cancer and Inflammation Program Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research Sponsored by the National Cancer Institute Frederick MD USA

6. Department of Human Molecular Genetics and Biochemistry Sackler School of Medicine Tel Aviv University Tel Aviv Israel

7. Genomic Medicine Institute, Lerner Research Institute Cleveland Clinic Cleveland OH USA

8. Department of Molecular Medicine Cleveland Clinic Lerner College of Medicine Case Western Reserve University Cleveland OH USA

9. Case Comprehensive Cancer Center Case Western Reserve University School of Medicine Cleveland OH USA

Funder

National Natural Science Foundation of China

Shanghai Municipal Education Commission

Shenzhen Graduate School, Peking University

Publisher

EMBO

Subject

Molecular Medicine

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